Assessment of the Immune Response of Clinically Infected Calves to Cryptosporidium parvum Infection

Cryptosporidium parvum (C. parvum) infection is one of the main causes diarrhea in calves. The current study assessed role blood biomarkers (acute-phase proteins (APPs), procalcitonin, neopterin, cytokines, and oxidative stress pathogenesis, diagnosis, prognosis calves naturally infected with C. parvum. Fifty-seven calves, aged from 10 to 45 days, were detected positive for allotted into diseased group; twenty healthy selected as a control group. Serum amyloid A, haptoglobin, tested groups. serum levels APPs, malondialdehyde increased, whereas antioxidant significantly decreased compared Moreover, all examined altered towards normal values following different treatment protocols. All highly effective discriminating between parvum-infected individuals. Furthermore, area under curve (AUC) showed that parameters had higher degree prognostic accuracy predicting response Our data suggest usefulness immune pathogenesis contributing diagnosis efficacy.